TEST DESCRIPTION
The Lumera Xpanded Solid Tumor Profile combines next-generation sequencing (NGS) with comprehensive molecular pathology case review and additional testing as needed. NGS analysis covers both DNA sequencing (523 genes) and RNA sequencing (55 genes), as well as copy number variation (CNV), tumor mutational burden (TMB), microsatellite instability (MSI), and RNA fusions and missplicing. This test can also incorporate HRR-HRD results in ovarian, peritoneal, fallopian tube and prostate tumor samples. Our expert pathology case review will determine complementary IHC, FISH, and molecular assays to be performed in addition to NGS for a fully customized report.
- Method: NGS & Pathology testing
- Sensitivity: ≥ 99%
- Specificty: 99.99%
- Mean Coverage: >1000x
- Turnaround Time: 10 business days or less
*This test will list out therapeutic associations
SPECIMEN REQUIREMENTS
1 FFPE Tumor Block (preferred)
Include 1 H&E slide if available
*We also accept core needle biopsies
ALSO ACCEPTED
25 Unstained Slides
4-5 micron sections
